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I have diabetes and high blood pressure and I'm very much concerned about having a heart attack in the future. I've started taking Altace and I'm quite pleased with the effects - my blood pressure is almost normal. I'm trying to maintain a healthier lifestyle as well and hopefully I will never experience any serious problems.

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Activation of the renin-angiotensin axis produces the biologically active peptide angiotensin II, which has several structural and hemodynamic effects, including stimulation of the sympathetic nervous system, vasoconstriction, increased aldosterone release and sodium retention, cardiac remodeling, smooth muscle cells growth and proliferation, vascular inflammation, generation of reactive oxygen species, endothelial dysfunction, renal fibrosis and so forth.

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