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Health outcomes associated with antihypertensive therapies used as first-line agents: a systematic review and meta-analysis.
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Activation of the renin-angiotensin axis produces the biologically active peptide angiotensin II, which has several structural and hemodynamic effects, including stimulation of the sympathetic nervous system, vasoconstriction, increased aldosterone release and sodium retention, cardiac remodeling, smooth muscle cells growth and proliferation, vascular inflammation, generation of reactive oxygen species, endothelial dysfunction, renal fibrosis and so forth.
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Discontinue therapy in patients with severe intolerance to IV therapy.
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Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise.
Reduced hypoglycemia risk with insulin glargine: a meta-analysis comparing insulin glargine with human NPH insulin in type 2 diabetes.
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