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Immunohistochemical assays were done using rabbit polyclonal antibody to human PSA (DakoCytomation, Glostrup, Denmark).

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Interaction of the human androgen receptor transactivation function with the general transcription factor TFIIF.

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Typically low testosterone PCa patients get some relief from estrogen patches that help to counter hypogonadism symptoms and combat the cancer.

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An anticancer drug that belongs to the family of drugs called gonadotropin-releasing hormones.

Dr Joy Yang holds a PhD in Microbiology and received postdoctoral training in Molecular Biology at the University of California, Davis.

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Bicalutamide binds to proteins called androgen receptors, which are found in some prostate cancer cells.

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BIC) is a drug of choice for the treatment of progressive androgen-dependent prostate cancer.

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ADT consists of treatment with a GnRH agonist, combined androgen blockade (GnRH analog plus antiandrogen), or, less commonly, bilateral orchiectomy.

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The court confirmed that the physician's actions were legal, although it did rule that the university medical center was required to continue providing treatments to the patient, provided that the patient continually complied with certain conditions.

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The patient, his partner, and the urologist should discuss treatment options in detail.

Treatment continued until the occurrence of unacceptable side effects or confirmed radiographic progression and the initiation of chemotherapy or an investigational agent.

Having a brother with prostate cancer is a higher risk than having a father with the disease.

The physician argued that if he were required to begin treating Mr.

Standard: A guideline statement is a standard if: (1) the health outcomes of the alternative interventions are sufficiently well known to permit meaningful decisions, and (2) there is virtual unanimity about which intervention is preferred.

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Men who have at least a 10-y life expectancyshould have an opportunity to make aninformed decision with their health careprovider about whether to be screened forprostate cancer.

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During treatment with bicalutamide, somnolence has been reported, and those patients who experience this symptom should observe caution when driving or operating machines.

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Testosterone levels in the body can be reduced either surgically or with drugs.

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These limitations may be overcome, however, by administering a very low dose (typically a few micrograms) of an isotopically labelled drug concomitantly with a therapeutic non-labelled oral dose.

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There is a huge stigma surrounding mental health problems, I do not agree with anything that encourages this and creates a sense of shame around taking meds to help with an illness.

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Gleave et al showed a significant improvement with 8-month neoadjuvant therapy compared with 3 months.

Caveats for modeling disease free survival after radical prostatectomy.

These agents have been demonstrated to improve sexual function in some men treated for prostate cancer.

About one-half of all men and one-third of all women in the US will develop cancer during their lifetimes.

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