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Due to the side effects I could only tolerate for one week opposed to 6 week regiman.
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Subjects are instructed to apply a thin layer of study medication to the treatment area, up to two packets (up to 500 mg) of product, avoiding the periocular areas, lips and nares.
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Do not cover the treated site with bandages or other closed dressings.
Other reported symptoms included erythema lasting up to 3 weeks (37%), mild to moderate pain (14%), transient burning sensation (10%), pruritis (6%), and post-inflammatory hypo- or hyperpigmentation (8%).
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Two weeks after, the PDT imiquimod 5% cream was applied to the treatment area once daily for three days per week.
Recently, imiquimod has been shown to promote the expression of cellular receptors that are associated with apoptosis.
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Time to complete clearing varied from 5 to 13 weeks based on both clinical and histopathologic findings.
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Additionally, the therapeutically effective amount is an amount sufficient to increase by at least about 30%, more preferably by at least 50%, most preferably by at least 90%, a clinically significant feature of pathology, such as cytokine production.
Although early basal cell carcinoma can be treated adequately by means of local excision, advanced and recurrent tumors are best managed by a multidisciplinary approach involving head and neck surgical oncologists, Mohs micrographic surgeons, reconstructive plastic surgeons, pathologists, prosthetists, and radiation oncologists.
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This is accounted for by the possible differences in their inactive ingredients such as color and flavor additives, and by the copyright and trademark regulations that does not allow for exact copies of the existing brand-name products.
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